annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
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Concerns about air quality have vexed Connecticut educators for decades.—Livi Stanford, Hartford Courant, 17 Apr. 2025 The current Doha Round, expanded to include developing nations, is stalled by vexing agriculture issues separating Africa and Europe.—Arthur I. Cyr, Chicago Tribune, 15 Apr. 2025 Among those vexed yesterday was the man who negotiated the first $100 million contract in 1998 and has gotten dozens more done since then, including this year’s record 15-year, $765 million contract Juan Soto signed with the Mets.—Kevin Acee, San Diego Union-Tribune, 3 Apr. 2025 Bird flu outbreaks that wiped out about 15 percent of the nation’s egg-laying chickens and drove wholesale egg prices to a peak of more than $8.50 a dozen in February have vexed grocery shoppers and prompted big breakfast chains to add surcharges to diners’ checks.—Martha C. White, New York Times, 26 Mar. 2025 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way
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