1
: a soiling or disfiguring mark : spot
2
: a mark of reproach : moral flaw
3
: a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (such as a complementary nucleic acid or a radiolabeled antibody) compare southern blot, western blot
blotted; blotting
1
: to spot, stain, or spatter with a discoloring substance
2
3
a
: to dry (something, such as writing) with an absorbing agent
hastily blotted her letter
b
: to remove with absorbing material
blotting up spilled water
1
: a lone backgammon man exposed to capture
2
archaic
: a weak or exposed point
Examples of blot in a Sentence
Noun (1)
the bribery scandal was a blot on his reputation
Verb
Don't rub the wine stain. Blot it dry with a paper towel.
Blot your lipstick with a tissue.
Recent Examples on the Web
Ashley Bardhan, Rolling Stone, 6 Feb. 2025
How To Get Pen Out Of Clothes Pet Stains
Remove any solids and blot wet areas with a paper towel.
—Mary Marlowe Leverette, Southern Living, 28 Oct. 2024
Katelyn Squiers, Better Homes & Gardens, 6 Apr. 2025
Spray the cleaner onto a clean white cloth, and then blot the stained area with the damp cloth.
—Kristi Kellogg, Architectural Digest, 31 Mar. 2025
See All Example Sentences for blot
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Noun
The ink blots of the past 20 years are dried all over Metal Gear Solid Delta.
—Ashley Bardhan, Rolling Stone, 6 Feb. 2025
How To Get Pen Out Of Clothes Pet Stains
Remove any solids and blot wet areas with a paper towel.
—Mary Marlowe Leverette, Southern Living, 28 Oct. 2024
Verb
To dry your bags properly, start by blotting both the interior and exterior with a towel to absorb excess moisture.
—Katelyn Squiers, Better Homes & Gardens, 6 Apr. 2025
Spray the cleaner onto a clean white cloth, and then blot the stained area with the damp cloth.
—Kristi Kellogg, Architectural Digest, 31 Mar. 2025
See All Example Sentences for blot
Cite this Entry
“Blot.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/blot. Accessed 22 Apr. 2025.
Copy CitationKids Definition
blot
1 of 2 nounblot
2 of 2 verb
blotted; blotting
2
3
4
: to dry with something absorbent
5
: to mark or become marked with a blot
Medical Definition
blot
noun
: a nitrocellulose sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and that is used to identify specific components of the spots by applying a suitable molecular probe (as a complementary nucleic acid or a radiolabeled antibody) see northern blot, southern blot, western blot
blot
transitive verb
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