bisphosphonate

noun

bis·​phos·​pho·​nate ˌbis-ˈfäs-fə-ˌnāt How to pronounce bisphosphonate (audio)
: any of a group of drugs that slow the breakdown of bone by osteoclasts

Examples of bisphosphonate in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
To ensure effectiveness, space your magnesium supplement at least 2 hours apart from bisphosphonates. Lindsay Curtis, Verywell Health, 9 Jan. 2025 Medications: Drugs like bisphosphonates and blood thinners can hinder bone healing. Paul Du Quenoy, Newsweek, 9 Jan. 2025 People with osteoporosis can take medications like bisphosphonates to lower the risk of fractures, Shapses said. Korin Miller, Health, 24 Dec. 2024 To prevent the effect, take bisphosphonates two hours before or after magnesium. Antibiotics: Taking magnesium with certain antibiotics, such as doxycycline and ciprofloxacin, can decrease the body's absorption of the drugs. Soma Mandal, Health, 2 Dec. 2024 See all Example Sentences for bisphosphonate 

Word History

Etymology

bis + phosphonic acid (an acid obtained from phosphine) + -ate entry 1

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of bisphosphonate was in 1961

Dictionary Entries Near bisphosphonate

Cite this Entry

“Bisphosphonate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/bisphosphonate. Accessed 23 Jan. 2025.

Medical Definition

bisphosphonate

noun
bis·​phos·​pho·​nate
ˌbis-ˈfäs-fə-ˌnāt
: any of a group of drugs (such as alendronate or etidronate) that slow the breakdown of bone by osteoclasts
… among the pharmacological approaches for treating osteoporosis, use of bisphosphonates increases bone mineral density and reduces the risk of vertebral fractures.Charles Marwick, The Journal of the American Medical Association

called also diphosphonate

Note: Bisphonates are analogs of pyrophosphate and contain two phosphate groups attached to a central carbon atom that replaces the oxygen atom in pyrophosphate.

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